CO-phylum: An Assembly-Free Phylogenomic Approach for Close Related Organisms

Biology – Quantitative Biology – Quantitative Methods

Scientific paper

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21 pages, 6 figures

Scientific paper

Phylogenomic approaches developed thus far are either too time-consuming or lack a solid evolutionary basis. Moreover, no phylogenomic approach is capable of constructing a tree directly from unassembled raw sequencing data. A new phylogenomic method, CO-phylum, is developed to alleviate these flaws. CO-phylum can generate a high-resolution and highly accurate tree using complete genome or unassembled sequencing data of close related organisms, in addition, CO-phylum distance is almost linear with p-distance.

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