Biology – Quantitative Biology – Populations and Evolution
Scientific paper
2006-02-13
Physical Review E 74, 041904 (2006)
Biology
Quantitative Biology
Populations and Evolution
18 pages, 11 figures, published in Physical Review E 74, 041904 (2006)
Scientific paper
10.1103/PhysRevE.74.041904
We investigate a stochastic version of a simple enzymatic reaction which follows the generic Michaelis-Menten kinetics. At sufficiently high concentrations of reacting species, the molecular fluctuations can be approximated as a realization of a Brownian dynamics for which the model reaction kinetics takes on the form of a stochastic differential equation. After eliminating a fast kinetics, the model can be rephrased into a form of a one-dimensional overdamped Langevin equation. We discuss physical aspects of environmental noises acting in such a reduced system, pointing out the possibility of coexistence of dynamical regimes where noise-enhanced stability and resonant activation phenomena can be observed together.
Fiasconaro Alessandro
Gudowska-Nowak Ewa
Ochab-Marcinek Anna
Spagnolo Bernardo
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