Biology – Quantitative Biology – Genomics
Scientific paper
2011-12-07
Biology
Quantitative Biology
Genomics
17 pages
Scientific paper
Chargaff once said that "I saw before me in dark contours the beginning of a grammar of Biology". In linguistics, "grammar" is the set of natural language rules, but we do not know for sure what Chargaff meant by "grammar" of Biology. Nevertheless, assuming the metaphor, Chargaff himself started a "grammar of Biology" discovering the so called Chargaff's rules. In this work, we further develop his grammar. Using new concepts, we were able to discovery new genomic rules that seem to be invariant across a large set of organisms, and show a fractal-like property, since no matter the scale, the same pattern is observed (self-similarity). We hope that these new invariant genomic rules may be used in different contexts since short read data bias detection to genome assembly quality assessment.
Beleza Yamagishi Michel Eduardo
Herai Roberto H.
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Anonymous visitor
Amazing finding. They proved that our genome, and like in the other animal as well, are being modulated by grammar rules, like a language.
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