BIM experiment module and its flight on MASER 10

Details BIM experiment module and its flight on MASER 10 BIM experiment module and its flight on MASER 10

Aug 2005

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2005esasp.590..487h&link_type=abstract

In: 17th ESA Symposium on European Rocket and Balloon Programmes and Related Research, 30 May - 2 June 2005, Sandefjord, Norway.

Biology

Microgravity, Biology

Scientific paper

The Biology In Microgravity (BIM) experiment module was flown in microgravity during 6 minutes on the sounding rocket MASER 10 on May 2, 2005. Swedish Space Corporation, Dutch Space and CCM developed the BIM module under contract from the European Space Agency (ESA). Two cell biology experiments were flown in the BIM module: ACTIN, Role of microgravity on actin metabolism in mammalian cells. Investigator: Prof. Dr. Johannes Boonstra, University of Utrecht (NL). AMUSE, Influence of micrograviy on activation of NF-κB, a principal regulator of inflammation and immunity. Investigator: Prof. Dr. Maikel Peppelenbosch, University of Groningen (NL). The BIM experiments were performed in 48 experiment units containing culture chambers and liquid storage reservoirs with additives, which were added to the culture chambers during the microgravity period of six minutes. Cultures in microgravity and on a 1xg reference centrifuge on-board the module were activated simultaneously with a reference on-ground. The experiment units were prepared hours before launch and were integrated in late access insert systems. The flight system was installed in the module via a hatch. The ground system, with the reference experiment units, was placed in an incubator. During the flight, when microgravity was achieved, all actions were performed to activate and, just before end of microgravity, fixate the experiment samples. The thermal control and the centrifuge worked properly. Due to a hard landing the module was severely damaged, nevertheless almost all experiments could be saved.

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