Bayesian Inference of Whole-Brain Networks

Details Bayesian Inference of Whole-Brain Networks Bayesian Inference of Whole-Brain Networks

2012-02-08

arxiv.org/abs/1202.1696v1

Biology

Quantitative Biology

Neurons and Cognition

10 pages, 2 figures

Scientific paper

In structural brain networks the connections of interest consist of white-matter fibre bundles between spatially segregated brain regions. The presence, location and orientation of these white matter tracts can be derived using diffusion MRI in combination with probabilistic tractography. Unfortunately, as of yet no approaches have been suggested that provide an undisputed way of inferring brain networks from tractography. In this paper, we provide a computational framework which we refer to as Bayesian connectomics. Rather than applying an arbitrary threshold to obtain a single network, we consider the posterior distribution of networks that are supported by the data, combined with an exponential random graph (ERGM) prior that captures a priori knowledge concerning the graph-theoretical properties of whole-brain networks. We show that, on simulated probabilistic tractography data, our approach is able to reconstruct whole-brain networks. In addition, our approach directly supports multi-model data fusion and group-level network inference.

Affiliated with

Also associated with

No associations

Rating

Bayesian Inference of Whole-Brain Networks does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Bayesian Inference of Whole-Brain Networks, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bayesian Inference of Whole-Brain Networks will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-64728