Statistics – Applications
Scientific paper
Oct 2005
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2005esasp1290..282s&link_type=abstract
In: Microgravity applications programme: Successful teaming of science and industry. Edited by Andrew Wilson, coordination: Benn
Statistics
Applications
Life Sciences, Bone Structure
Scientific paper
Loss of bone mass and structure is one of the most prominent risk factors associated with human spaceflight. The main objective of this multifaceted MAP project was therefore to establish a precise diagnostic method for quantifying alterations in the structural composition of human trabecular bone. Tools based on evaluation of 2-D Computed Tomography (CT) and 3-D micro-CT (μCT) images by measures of complexity were developed. These tools quantify different aspects of spatial bone architecture. The measures, methods and results were validated by comparison with conventional histomorphometry and biomechanical testing. In order to visualise the obtained μCT data, special tools had to be developed able to handle huge amounts of data.
Asbeck Christian
Beller Gisela
Felsenberg Dieter
Fratzl Peter
Gowin Wolfgang
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