Acid-labile amino acid precursors in the Murchison meteorite. I. Chromatographic fractionation.

Details Acid-labile amino acid precursors in the Murchison meteorite. I. Chromatographic fractionation. Acid-labile amino acid precursors in the Murchison meteorite. I. Chromatographic fractionation.

Dec 1976

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1976orli....7..337c&link_type=abstract

Origins of Life, Volume 7, Issue 4, pp.337-342

Computer Science

13

Scientific paper

The amino acid content of a hot water extract of the Murchison meteorite can be increased by over 100 per cent by subjecting the extract to acid hydrolysis. The acid-labile compounds in the extract that account for this increase were fractionated by column chromatography on a cation exchange resin. Sevently mole per cent behaved as neutral or acidic compounds and were eluted from the column with an initial water wash. The remaining 30 mole per cent (basic precursors) were retained on the column and were eluted with the free amino acids by aqueous NH4OH. The acid-labile amino acid precursors in the water eluate could be retained and further fractionated on an anion exchange column, indicating that they are acidic compounds.

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