A quantitative measurement of spatial order in ventricular fibrillation

Nonlinear Sciences – Pattern Formation and Solitons

Scientific paper

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20 pages with 13 Postscript figures. To appear in the J. Cardiovascular Electrophysiology, 1993

Scientific paper

As an objective measurement of spatial order in ventricular fibrillation (VF), spatial correlation functions and their characteristic lengths were estimated from epicardial electrograms of pigs in VF. The correlation length of the VF in pigs was found to be approximately 4-10 mm, varying as fibrillation progressed. The degree of correlation decreased in the first 4 seconds after fibrillation then increased over the next minute. The correlation length is much smaller than the scale of the heart, suggesting that many independent regions of activity exist on the epicardium at any one time. On the other hand, the correlation length is 4 to 10 times the interelectrode spacing, indicating that some coherence is present. These results imply that the heart behaves during VF as a high-dimensional, but not random, system involving many spatial degrees of freedom, which may explain the lack of convergence of fractal dimension estimates reported in the literature. Changes in the correlation length also suggest that VF reorganizes slightly in the first minute after an initial breakdown in structure.

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