A modular Fibonacci sequence in proteins

Details A modular Fibonacci sequence in proteins A modular Fibonacci sequence in proteins

2004-09-30

arxiv.org/abs/q-bio/0409038v1

Biology

Quantitative Biology

Genomics

11 pages, 1 figure, 2 tables

Scientific paper

Protein-fragment seqlets typically feature about 10 amino acid residue positions that are fixed to within conservative substitutions but usually separated by a number of prescribed gaps with arbitrary residue content. By quantifying a general amino acid residue sequence in terms of the associated codon number sequence, we have found a precise modular Fibonacci sequence in a continuous gap-free 10-residue seqlet with either 3 or 4 conservative amino acid substitutions. This modular Fibonacci sequence is genuinely biophysical, for it occurs nine times in the SWISS-Prot/TrEMBL database of natural proteins.

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