A model of host response to a multi-stage pathogen

Biology – Quantitative Biology – Populations and Evolution

Scientific paper

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22 pages, no figures

Scientific paper

We model the immune surveillance of a pathogen which passes through $n$
immunologically distinct stages. The biological parameters of this system
induce a partial order on the stages, and this, in turn, determines which
stages will be subject to immune regulation. This corresponds to the system's
unique asymptotically stable fixed point.

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