Computer Science – Data Structures and Algorithms
Scientific paper
2005-12-04
Computer Science
Data Structures and Algorithms
Scientific paper
This paper describes a linear-time algorithm that finds the longest stretch in a sequence of real numbers (``scores'') in which the sum exceeds an input parameter. The algorithm also solves the problem of finding the longest interval in which the average of the scores is above a fixed threshold. The problem originates from molecular sequence analysis: for instance, the algorithm can be employed to identify long GC-rich regions in DNA sequences. The algorithm can also be used to trim low-quality ends of shotgun sequences in a preprocessing step of whole-genome assembly.
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