Evolution of the genetic code from the GC- to the AGUC-alphabet

Biology – Quantitative Biology – Populations and Evolution

Scientific paper

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Scientific paper

A hypothesis of the evolution of the genetic code is proposed, the leading
mechanism of which is the nucleotide spontaneous damage leading to
AT-enrichment of the genome. The hypothesis accounts for stability of the
genetic code towards point mutations, the presence of code dialects, and the
symmetry of the genetic code table.

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