Role of calcium and noise in the persistent activity of an isolated neuron

Details Role of calcium and noise in the persistent activity of an isolated neuron Role of calcium and noise in the persistent activity of an isolated neuron

2004-06-03

arxiv.org/abs/q-bio/0406010v1

Biology

Quantitative Biology

Neurons and Cognition

date de redaction: 30/5/2004

Scientific paper

The activity of an isolated and auto-connected neuron is studied using Hodgkin--Huxley and Integrate-and-Fire frameworks. Main ingredients of the modeling are the auto-stimulating autaptic current observed in experiments, with a spontaneous synaptic liberation noise and a calcium--dependent negative feedback mechanism. The distributions of inter-spikes intervals and burst durations are analytically calculated, and show a good agreement with experimental data.

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