Exact solution of a two-type branching process: Clone size distribution in cell division kinetics

Details Exact solution of a two-type branching process: Clone size distribution in cell division kinetics Exact solution of a two-type branching process: Clone size distribution in cell division kinetics

2009-08-04

arxiv.org/abs/0908.0484v1

Journal of Statistical Mechanics P07028 (2010)

Biology

Quantitative Biology

Populations and Evolution

16 pages

Scientific paper

10.1088/1742-5468/2010/07/P07028

We study a two-type branching process which provides excellent description of experimental data on cell dynamics in skin tissue (Clayton et al., 2007). The model involves only a single type of progenitor cell, and does not require support from a self-renewed population of stem cells. The progenitor cells divide and may differentiate into post-mitotic cells. We derive an exact solution of this model in terms of generating functions for the total number of cells, and for the number of cells of different types. We also deduce large time asymptotic behaviors drawing on our exact results, and on an independent diffusion approximation.

Affiliated with

Also associated with

No associations

Rating

Exact solution of a two-type branching process: Clone size distribution in cell division kinetics does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Exact solution of a two-type branching process: Clone size distribution in cell division kinetics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Exact solution of a two-type branching process: Clone size distribution in cell division kinetics will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-557374