Biology – Quantitative Biology – Populations and Evolution
Scientific paper
2011-04-23
Biology
Quantitative Biology
Populations and Evolution
13 pages, 2 figures
Scientific paper
Understanding the origin of infectious diseases provides scientifically based rationales for implementing public health measures that may help to avoid or mitigate future epidemics. The recent ancestors of a pandemic virus provide invaluable information about the set of minimal genomic alterations that transformed a zoonotic agent into a full human pandemic. Since the first confirmed cases of the H1N1 pandemic virus in the spring of 2009, several hypotheses about the strain's origins have been proposed. However, how, where, and when it first infected humans is still far from clear. The only way to piece together this epidemiological puzzle relies on the collective effort of the international scientific community to increase genomic sequencing of influenza isolates, especially ones collected in the months prior to the origin of the pandemic.
Chan Joseph
Hernandez Carlos Xavier
Khiabanian Hossein
Rabadan Raul
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