A schematic age-structured compartment model of the impact of antiretroviral therapy on HIV incidence and prevalence

Details A schematic age-structured compartment model of the impact of antiretroviral therapy on HIV incidence and prevalence A schematic age-structured compartment model of the impact of antiretroviral therapy on HIV incidence and prevalence

2005-01-06

arxiv.org/abs/q-bio/0501009v1

Biology

Quantitative Biology

Populations and Evolution

29 pages, 14 figures

Scientific paper

A simple deterministic model is proposed to represent the basic aspects concerning the effects of different antiretroviral treatment schedules on HIV incidence and prevalence of affected populations. The model mimics current treatment guidelines applied in Brazil. However, the model does not intend to fit the data with any acceptable degree of accuracy since uncertainties on the values of the parameters and on the precise effect of the treatment put some limits on the practical implications of our model from which only orders of magnitude and some qualitative effects can be deduced. So, this paper intends to provide a conceptual and mechanistic understanding of the possible long term effects of treatment on the dynamics of HIV transmission. According to the model, the effect of the treatment depends on the level of sexual activity of the subpopulations considered, being more pronounced on the subpopulations with the highest sexual activity levels. Also, inefficient treatment can be prejudicial depending on the level of sexual activity and on the capacity to provide adequate treatment coverages to the population affected.

Affiliated with

Also associated with

No associations

Rating

A schematic age-structured compartment model of the impact of antiretroviral therapy on HIV incidence and prevalence does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with A schematic age-structured compartment model of the impact of antiretroviral therapy on HIV incidence and prevalence, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A schematic age-structured compartment model of the impact of antiretroviral therapy on HIV incidence and prevalence will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-293205