Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers

Details Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers Mathematical and numerical analysis of a model for anti-angiogenic therapy in metastatic cancers

2010-09-16

arxiv.org/abs/1009.3173v1

Mathematics

Analysis of PDEs

Nombre de pages : 29

Scientific paper

We introduce and analyze a phenomenological model for anti-angiogenic therapy in the treatment of metastatic cancers. It is a structured transport equation with a nonlocal boundary condition describing the evolution of the density of metastasis that we analyze first at the continuous level. We present the numerical analysis of a lagrangian scheme based on the characteristics whose convergence establishes existence of solutions. Then we prove an error estimate and use the model to perform interesting simulations in view of clinical applications.

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