Statistics – Applications
Scientific paper
2012-02-27
Annals of Applied Statistics 2011, Vol. 5, No. 4, 2326-2358
Statistics
Applications
Published in at http://dx.doi.org/10.1214/10-AOAS402 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Ins
Scientific paper
10.1214/10-AOAS402
In biological experiments researchers often have information in the form of a graph that supplements observed numerical data. Incorporating the knowledge contained in these graphs into an analysis of the numerical data is an important and nontrivial task. We look at the example of metagenomic data---data from a genomic survey of the abundance of different species of bacteria in a sample. Here, the graph of interest is a phylogenetic tree depicting the interspecies relationships among the bacteria species. We illustrate that analysis of the data in a nonstandard inner-product space effectively uses this additional graphical information and produces more meaningful results.
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