Extreme genetic code optimality from a molecular dynamics calculation of amino acid polar requirement

Details Extreme genetic code optimality from a molecular dynamics calculation of amino acid polar requirement Extreme genetic code optimality from a molecular dynamics calculation of amino acid polar requirement

2007-12-20

arxiv.org/abs/0712.3332v2

Biology

Quantitative Biology

Populations and Evolution

4 pages, 2 figures. Revised manuscript describes signature of statistical proteins

Scientific paper

A molecular dynamics calculation of the amino acid polar requirement is presented and used to score the canonical genetic code. Monte Carlo simulation shows that this computational polar requirement has been optimized by the canonical genetic code more than any previously-known measure. These results strongly support the idea that the genetic code evolved from a communal state of life prior to the root of the modern ribosomal tree of life.

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