Mathematics – Probability
Scientific paper
Dec 1983
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1983orli...13..139p&link_type=abstract
Origins of Life, Volume 13, Issue 2, pp.139-146
Mathematics
Probability
3
Scientific paper
The frequency of amino acid replacements in families of typical proteins has been elegantly analyzed by Argyle (1980) showing that the most frequent replacements involve a conservation of the amino acid chemical properties. The cyclic arrangement of the twenty amino acids resulting from the most frequent replacements has been described as an amino acid chemical ring. In this work, a novel amino acid replacement frequency ring is proposed, for which a conservation of over 90% of the most general physico-chemical properties can be deduced. The amino acid chemical similarity ring is also analyzed in terms of the genetic code base probability changes, showing that the discrepancy that exists between the standard deviation value of the amino acid replacement frequency matrix and its respective ideal value is almost equal to that deduced from the corresponding base codon replacement probability matrices. These differences are finally evaluated and discussed in terms of the restrictions imposed by the structure of the genetic code and the physico-chemical dissimilarities between some codons of amino acids which are chemically similar.
Pieber Maria
Tohác José
No associations
LandOfFree
Code Dependent Conservation of the Physico-Chemical Properties in Amino Acid Substitutions does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Code Dependent Conservation of the Physico-Chemical Properties in Amino Acid Substitutions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Code Dependent Conservation of the Physico-Chemical Properties in Amino Acid Substitutions will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-1805466