Other
Scientific paper
Mar 1987
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1987sci...235.1173w&link_type=abstract
Science, Volume 235, Issue 4793, pp. 1173-1178
Other
40
Scientific paper
Phosphate esters and anhydrides dominate the living world but are seldom used as intermediates by organic chemists. Phosphoric acid is specially adapted for its role in nucleic acids because it can link two nucleotides and still ionize; the resulting negative charge serves both to stabilize the diesters against hydrolysis and to retain the molecules within a lipid membrane. A similar explanation for stability and retention also holds for phosphates that are intermediary metabolites and for phosphates that serve as energy sources. Phosphates with multiple negative charges can react by way of the monomeric metaphosphate ion PO3{}- as an intermediate. No other residue appears to fulfill the multiple roles of phosphate in biochemistry. Stable, negatively charged phosphates react under catalysis by enzymes; organic chemists, who can only rarely use enzymatic catalysis for their reactions, need more highly reactive intermediates than phosphates.
No associations
LandOfFree
Why Nature Chose Phosphates does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Why Nature Chose Phosphates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Why Nature Chose Phosphates will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-1599514