Oligomerization reactions of ribonucleotides: The reaction of the 5'-phosphorimidazolide of nucleosides on montmorillonite and other minerals

Details Oligomerization reactions of ribonucleotides: The reaction of the 5'-phosphorimidazolide of nucleosides on montmorillonite and other minerals Oligomerization reactions of ribonucleotides: The reaction of the 5'-phosphorimidazolide of nucleosides on montmorillonite and other minerals

Nov 1992

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1992oleb...22..369f&link_type=abstract

Origins of Life and Evolution of the Biosphere, Volume 22, Issue 6, pp.369-381

Other

17

Scientific paper

The reaction of ImpA in the presence of Na+-montmorillonite 22A or Na+-Volclay in aqueous, pH 8 solution gives a 50 60% yield of dimers and trimers (pA)2 and (pA)3. The ratio of 3',5'-phosphodiester bond formation is twice as great as 2',5'-bond formation. The reaction requires the presence of Mg2+ and is inhibited by 0.4 M imidazole. N-methylimidazole enhances the rate of the reaction but does not cause major changes in yield or product composition. Higher yields were obtained when Li+- or Ca2+-montmorillonites were used in place of Na+-montmorillonite. Little or no phosphodiester bond formation was observed with Mg2+- or Al3+-montmorillonite. Montmorillonites other than 22A and Volclay exhibited little or no catalysis. In addition, little or no catalysis was exhibited in ferrugenous smectite, nontronite, allophane, imogolite or sepiolite. Oligomers were also formed by the reaction of ImpG, 2-methylImpG, ImpC and ImpU in the presence of Na+-montmorillonite. The pyrimidine nucleotides gave significantly lower yields of oligomers.

Affiliated with

Also associated with

No associations

Rating

Oligomerization reactions of ribonucleotides: The reaction of the 5'-phosphorimidazolide of nucleosides on montmorillonite and other minerals does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Oligomerization reactions of ribonucleotides: The reaction of the 5'-phosphorimidazolide of nucleosides on montmorillonite and other minerals, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oligomerization reactions of ribonucleotides: The reaction of the 5'-phosphorimidazolide of nucleosides on montmorillonite and other minerals will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-1555180